The band's sixth album, Highway to Hell, was produced by Robert Lange and released in 1979. It became the first AC/DC LP to break into the US top 100, eventually reaching #17,and it propelled AC/DC into the top ranks of hard rock acts. Highway to Hell put increased emphasis on backing vocals but still featured AC/DC's signature sound: loud, simple, pounding riffs and grooving backbeats. The final track, "Night Prowler", has two breaths in quick succession at the start of the song, intended to create a tone of fear and loathing.

Bon Scott's Death (1980)

"Night Prowler" contained all the new elements of Highway to Hell. The song finishes with Bon Scott saying "Shazbot, Nanu Nanu!". Strangely Bon Scott's last words on his last album were Shazbot, Nanu Nanu. This was an expression used by character Mork, played by Robbin Williams on the popular TV show Mork And Mindy. Shazbot, Nanu Nanu meant good bye.

On February 19, 1980, Bon Scott reportedly passed out after a night of heavy drinking in London. He was left in a car owned by an acquaintance of his named Alistair Kinnear. The following morning, Kinnear rushed him to King's College Hospital in Camberwell, where Scott was pronounced dead on arrival. Although common folklore claims that pulmonary aspiration of vomit was the cause of Scott's death, the official cause was listed as "acute alcohol poisoning" and "death by misadventure". Scott's family buried him in Fremantle, Western Australia, the area to which they had emigrated when he was a child Inconsistencies in the official accounts of Scott's death have been cited in conspiracy theories, which suggest that Scott died of a heroin overdose, or was killed by exhaust fumes redirected into the car, or that Kinnear did not exist. Additionally, Scott was asthmatic, and the temperature was below freezing on the morning of his death.

Finding A New Singer

Following Scott's death, the band briefly considered quitting; they eventually concluded, however, that Scott would have wanted AC/DC to continue, and various candidates were considered for his replacement including Buzz Shearman, ex-Moxy member, who was not able to join due to vocal problems, and ex-Back Street Crawler vocalist Terry Slesser, who decided not to join an established band. The remaining AC/DC members finally decided on ex-Geordie singer Brian Johnson.

Angus Young later recalled, "I remember Bon playing me Little Richard, and then telling me the story of when he saw Brian singing." He says about that night, "There's this guy up there screaming at the top of his lungs and then the next thing you know he hits the deck. He's on the floor, rolling around and screaming. I thought it was great, and then to top it off—you couldn't get a better encore—they came in and wheeled the guy off!'" Later that night, Johnson would be diagnosed with appendicitis, which was the cause of his writhing around on stage.

For the audition, Johnson sang "Whole Lotta Rosie" from Let There Be Rock, and Ike & Tina Turner's "Nutbush City Limits". He was hired a few days after the audition.

Brian Johnson Era (1980–present)

With Brian Johnson the band completed the songwriting that they had begun with Bon Scott for the album Back in Black. Recording took place at Compass Point Studios in the Bahamas a few months after Scott's death. Back in Black, produced by Mutt Lange and recorded by Tony Platt, became their biggest-selling album and a hard-rock landmark; hits include "Hells Bells", "You Shook Me All Night Long", and the title track "Back in Black". The album was certified platinum a year after its release, and by 2006 it had sold more than 22 million copies in the United States. The album reached #1 in the UK and #4 in the US, where it spent 131 weeks in the top ten.

The following album, 1981's For Those About to Rock We Salute You, also sold well and was positively received by critics. The album featured two of the band's most popular singles: "Let's Get It Up" and the title track, "For Those About to Rock", which reached #13 and #15 in the UK. The band split with Lange for their self-produced 1983 album, Flick of the Switch, in an effort to recover the rawness and simplicity of their early albums.